Resolving precise details with 700 μm spatial resolution

• Finest (1.12mm×1.12mm) lutetium oxyorthosilicate (LSO) crystal needles provide precise signal localization preserving spatial information in raw data
• Tera-Tomo™ 3D PET iterative reconstruction with real-time Monte Carlo based physical modelling unveiling the tiniest details on the image
• Large ring diameter and statistical depth of interaction compensation offers homogeneous image quality over the entire field of view

Uncompromised applications with very low level of radioactivity

• Thick LSO crystals for excellent sensitivity
• Short (3 ns) coincidence time window necessary for improved signal to noise ratio
• Advanced corrections (random, scatter, LSO background etc.) ensuring quantification at low activity levels
• Best Minimal Detectable Activity on the market: 60 Bq (1.6 nCi)
• Dedicated feature of the iterative Tera-Tomo™ 3D PET reconstruction engine ensures precise quantification at very low levels of activity 
• Analytic reconstruction option (FBP) with attenuation and scatter correction available for quantitative reconstruction of low activities close to regions with significantly higher activity 
• Inherently optimized for longitudinal studies e.g. long-term cell tracking.

Coping with count rate: mastering studies with high dose

• Multichannel read-out electronics with ultra-fast data processing and advanced dead-time correction
• Exceptional count rate performance – peak Noise Equivalent Count Rate (NECR) for mouse is up to 1300 kcps @ 80 MBq (2.16 mCi)
• Accurate and reproducible uptake values ensured by very high level of quantification accuracy up to 80 MBq (2.16 mCi) and beyond, with quantification error of ±2%
• Suitable for dynamic imaging of large animals or for dynamic scanning of up to four mice or two rats simultaneously
• Optimal for imaging of isotopes with short half-life (¹¹C, ¹³N, ¹⁵O, etc.)

Largest transaxial field of view

• Wide bore diameter up to 16 cm allowing free access to the animals
• Large transaxial field of view up to 12 cm
• Excellent homogeneity over the entire field of view
• Suitable for various animal models from tiny mouse (25 g) to large rabbits (6.5 kg)
• Simultaneous multiple animal imaging (up to 4 mice or 2 rats) with individual physiological monitoring

Excellent image quality and quantitation accuracy with the Tera-Tomo™ image reconstruction

Our proprietary iterative reconstruction engine, used in both clinical and preclinical systems ensures quantitative results with excellent resolution for all PET isotopes. 

• The Tera-Tomo™ 3D PET reconstruction engine along with the most advanced detector calibration algorithms ensure a very high level of quantification accuracy through the entire dynamic range of the system. The quantification error of +/- 2% results in accurate and reproducible uptake values 
• 3D iterative reconstruction applying deep Monte Carlo based physical modelling of particle-level interaction from positron emission to detection
• Advanced corrections for energy, time, dead-time and random events and positron range
• CT or MR based attenuation and scatter correction
• Automated workflow with 4D multiparametric PET reconstruction for fast kinetic analysis of dynamic acquisitions

High power CT with large field-of-view and high resolution

• Up to 80 W X-ray power together with the largest field of views (12 cm transaxial and 45 cm helical scan range) enables high performance scanning of even large or multiple animals
• Very high throughput: fast scanning with real-time image reconstruction combined with multiple animal imaging capability
• Variable magnification (up to x7.6) for high-resolution imaging even with 10 μm isotropic voxel size
• Iterative image reconstruction for low-noise and low-dose imaging
• Ultra-low-dose protocol for follow-up studies with less than 1 mGy whole-body dose to the animal for reliable longitudinal studies, e.g. following tumour growth or therapy response
• Imaging with cardiac and respiratory gating for reducing motion artifacts and for analysis of cardiac and pulmonary function.