Kyung Jun Kang et al., MDPI Journal of Imaging, 2021
For this purpose, researchers use micro-PET (µPET), which is a small-animal dedicated system. Most µPET vendors provide a single bed, thereby allowing imaging of only a single animal at a time. Large-scale research involving many objects thus requires tremendous time and use of radioactivity.
Recently, Mediso developed a multi-bed system dedicated to the nanoScan scanners with the contribution of Tim Witney and his team at UCL and KCL, where the initial validity for research has been investigated. Greenwood et al. (The Journal of Nuclear Medicine) tested the four-bed mouse system using 2-deoxy-2-(18F)fluoro-D-glucose (18F-FDG) in phantom and normal mice and reported a quantitative accuracy similar to that of a single-bed. To date, however, few studies have focused on the validity of oncological and neurological PET imaging of the four-mice bed system.
This study aimed to evaluate the image qualities of oncological and neurological PET imaging using a novel four-mice bed system.
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