Features & Benefits
Resolving precise details with 700 μm spatial resolution
- Finest lutetium oxyorthosilicate (LSO) crystal needles provide precise signal localization preserving spatial information in raw data
- Tera-Tomo™ 3D PET iterative reconstruction with real-time Monte Carlo based physical modelling unveiling the tiniest details on the image
- Large ring diameter and statistical depth of interaction compensation offer homogeneous image quality over the entire field of view
Uncompromised applications with very low level of radioactivity
- Thick LSO crystals for excellent sensitivity
- Advanced corrections (random, scatter, LSO background etc.) ensuring quantification at low activity levels
- Best minimal detectable activity on the market: 60 Bq (1.6 nCi)
- Inherently optimized for longitudinal studies e.g. long-term cell tracking
Coping with count rate: mastering studies with high dose
- Multichannel read-out electronics with ultra-fast data processing and advanced dead-time correction
- Exceptional count rate performance – peak noise equivalent count rate (NECR) for mouse is 850 kcps @ 60 MBq
- Fully quantitative at 60 MBq (1.6 mCi) and beyond
- Suitable for dynamic imaging of large animals or for dynamic scanning of up to four mice simultaneously
- Optimal for imaging of isotopes with short half-life (11C, 13N, 15O etc.)
Largest transaxial field of view
- Wide bore diameter of 16 cm allowing open access to the animals
- Large transaxial field of view of 12 cm
- Excellent homogeneity over the entire field of view
- Suitable for various animal models from tiny mouse to large rabbits (6.5 kg)
- Simultaneous multiple animal imaging (up to 4 mice or 2 rats) with individual physiological monitoring function
Excellent image quality and quantitation accuracy with the Tera-Tomo™ image reconstruction
- 3D iterative reconstruction applying deep Monte Carlo based physical modelling of particle-level interaction from positron emission to detection
- Advanced corrections for energy, time, dead-time and random events and positron range
- CT or MR based attenuation and scatter correction
- Readily available acquisition and reconstruction protocols optimized for wide range of applications
- Automated workflow with 4D multiparametric PET reconstruction for fast kinetic analysis of dynamic acquisitions
High power CT with large field-of-view and high resolution
- Up to 80 W X-ray power enables high-performance scanning even for large or multiple animals
- Variable magnification for high-resolution imaging with 10 μm isotropic voxel size
- Very high throughput: fast scanning with real-time image reconstruction combined with multiple animal imaging capability
- Iterative image reconstruction for low-noise and low-dose imaging
- Ultra-low-dose protocol for follow-up studies with only 1 mSv whole-body dose to the animal
- Imaging with cardiac and respiratory gating
Applications
Publications
Images
Specification
16 cm
12 cm
10 cm
Mouse, rat, marmoset, guinea pig, rabbit
up to 4 x 60 g mice 2 x 500 g rats
LSO (1.12 x 1.12 x 13 mm)
0.7 mm
1.25 mm
8%
850 kcps @ 60 MBq
250 kcps @ 60 MBq
up to 80 W
16 cm
12 cm
10 cm
mouse, rat, marmoset, guinea pig, rabbit
up to 4 x 60 g mice 2 x 500 g rats
modified Feldkamp-type for real-time reconstruction, iterative for low-dose and low-noise applications
30 μm at 10 μm voxel size
down to 1 mSv for whole-body mouse
Maintenance-free permanent magnet with 1 Tesla field strength
Zero (5 Gauss line is inside the cover)
Integrated RF shielding, no need for Faraday cage
Volume coils: whole-body mouse, whole-body rat; Surface coils: mouse brain, rat brain
100 μm in vivo <100 µm ex vivo
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